Blood cells formed in the bone marrow start out as stem cells. Blood components and preparation linkedin slideshare. Ppt blood components powerpoint presentation free to. Please help improve this article by adding citations to reliable sources. Red blood cells circulate for about 4 months, platelets for about 9 days, and. Blood plasma contain 55% of the blood and 92% of the plasma is water. This bundle is for the complete lesson on blood and blood components for a human anatomy and physiology course. If youre seeing this message, it means were having trouble loading external resources on our website. Circular is an exten sion of container labels, as the space on those labels is limited. Blood and blood components 12 considering that the government of finland has expressed the desire to participate in the operation of the abovementioned european blood bank, resolves. The blood in our circulatory system is a watery based fluid and consists of two basic components.
Blood is a circulating tissue composed of fluid, plasma, and cells. As different blood components have different relative density, sediment rate and size they can be separated when centrifugal force is applied. An analysis of the concentration of red blood cells, white blood cells, and platelets in the blood. Plasma the plasma is the light yellow liquid portion of the blood and is about 90% water. The first successful transfusion of human blood, as a treatment for postpartum. The cellular components of blood are erythrocytes red blood cells, or rbcs, leukocytes white blood cells, or wbcs, and thrombocytes platelets. Science biology human biology circulatory and pulmonary systems. Overview of blood boundless anatomy and physiology. A leukocytereduced component is defined as one with less than 5.
Pdf evaluation of the interaction of vanadium with. It contains erythrocytes, leucocytes, thrombocytes platelets and plasma. Many substances required by the body can be found in the blood plasma. Circular of information for the use of human blood and. The average adult has a blood volume of roughly 5 litres 11 us pt or 1. Ppt blood components powerpoint presentation free to view. Blood and blood components are biological products and living human tissue intended for use in patient treatment. Considerable inequalities remain in access to medical products of human origin, even blood and blood components, between and within countries and regions. The whole blood which is a mixture of cells, colloids and crystalloids can be separated into different blood components namely packed red blood cell prbc.
This bundle contains a powerpoint presentation of blood and the components of blood f. An acceptable circular of information for the use of. Blood accounts for 7% of the human body weight, with an average density around 1060 kgm 3, very close to pure waters density of kgm 3. Pdf overview of blood components and their preparation. These items are sold separately in my store but im offering the complete lesson at a discounted price. This circular was prepared jointly by aabb, the american red cross, americas blood centers, and the armed ser vices blood program. In increasing order, the specific gravity of blood components is plasma, platelets, leucocytes buffy coat bc and. Apr 29, 2020 blood makes up about 8% of the human body weight. Special machines that analyze the different components of blood in less than a. Blood is made up of multiple components, including red blood cells, white blood cells, platelets, and plasma. Circular of information for the use of human blood and blood components hereafter referred to as. Oct 15, 2014 4 components of blood and their functions 1.
Red blood cells erythrocytes carry oxygen from the lungs to the rest of the body. Guidelines on management of blood and blood components as. The volume percentage of all blood cells in the whole blood is about 45% of adults hematocrit. This essential fluid carries out the critical functions of transporting oxygen and nutrients to our cells and getting rid of carbon dioxide, ammonia, and other waste products. These help fight infections and aid in the immune process. Explain why it is classified as a connective tissue. Its composition and function the blood in our circulatory system is a watery based fluid and consists of two basic components. It transports all the substances such as blood cells, hormones, nutrients and excretory substances throughout the body. Bone marrow stem cells develop into red blood cells, white blood cells, and platelets. Pdf the whole blood which is a mixture of cells, colloids and crystalloids can be separated into different blood components namely packed red blood. Blood components should be aboidentical with the transfusion recipient, although situations frequently arise in which this is not possible table 19. In the systole phase of the cardiac cycle, the heart ventricles contract beat and pump blood into the arteries. The transfusable components that can be derived from donated blood are red cells, platelets, plasma, cryoprecipitated ahf cryo, and granulocytes. In hospitals the blood is collected and separated into major components before transfusion.
Plasma, white blood cells, red blood cells, platelets. These blood cells which are also called corpuscles or formed elements consist of. Circular of information for the use of human blood and blood aabb federal law prohibits dispensing the blood and blood components described in this circular without a prescription. Plasma, in which the blood cells are suspended, including. The complete blood count is the calculation of the cellular formed elements of blood. The food and drug administration recognizes this circular of information as an acceptable extension of container labels. Who technical report series no 858, annex 1 adopted by ecbs 1994 pdf, 773kb. Sbv reactivity was determined using an hplchgafs hyphenated system. When you are wounded, blood comes out of that wound quickly.
An introduction to blood components and component therapy. Blood is a mobile connective tissue composed of a fluid, the plasma and the cells, the blood corpuscles. Components of human blood percentages free pdf ebook. These carry oxygen from the lungs to the rest of the body white blood cells leukocytes.
Who requirements for the collection, processing and quality control of blood, blood components and plasma derivatives. As the stem cell matures, several distinct cells evolve. Rbc and granulocyte components, then the donors rbcs must be compatible with the recipients plasma table 19. Annex 3 guidelines on management of blood and blood components as essential medicines 1. Blood and blood components as biological therapeutic products 5 3. The complete blood count cbc is one of the most commonly ordered blood tests. By volume, the rbcs constitute about 45% of whole blood, the plasma about 54. An additional component, white cells, is often removed from donated blood before transfusion. Blood pressure readings measure systolic and diastolic pressures as the heart goes through the cardiac cycle. The circular of information for the use of human blood and blood components hereafter referred to as circular is an extension of container labels, as the space on those labels is limited. Circular of information for the use of human blood and blood components page content this webpage provides the background information for compliance with fda requirements under 21 cfr 606.
Blood components are depleted of leukocytes by means of filtration. Physick, performs the first human blood transfusion, although he does not publish this. Although scientific evidence shows that blood products have never been safer since the introduction of several measures in the last years, uncertainty still persists in the public. Overview of blood components and their preparation ncbi.
Human blood consists of about 22 percent solids and 78 percent water. Blood and blood components are biologic products and, in the form of cellular products, living human tissue intended for use in patient treatment. Biological medicines such as blood products and related in vitro diagnostic tests are lifesaving components of every day medical practice worldwide. Blood pressure is the force at which blood exerts pressure against artery walls as it circulates throughout the body. An acceptable circular of information for the use of human. References 1 and 4 give extensive information on enzymes, hormones, vitamins, and other blood constituents. People requires transfusion in various conditions such. The components of blood include red blood cells, white blood cells, platelets, and plasma. The table covers elements and compounds of relatively low molecular weight.
Although scientific evidence shows that blood products have never been safer since the introduction of several measures in the last years, uncertainty still. Whole blood contains red cells, white cells, and platelets 45% of volume. Which statement correctly describes the activities of the 2 red blood cells can move, but white blood cells cannot. Leukocyte removal should be performed while the cells are still intact by filtering.
Circular of information for the use of human blood and blood. The whole blood which is a mixture of cells, colloids and crystalloids can be separated into different blood components namely packed red blood cell prbc concentrate, platelet concentrate, fresh. Blood and blood components safety, quality, training and. Principles on the donation and management of blood, blood. A stem cell or hematopoietic stem cell is the first phase of all blood cells. The whole blood which is a mixture of cells, colloids and crystalloids can be separated into different blood components namely packed red blood cell prbc concentrate, platelet concentrate, fresh frozen plasma and cryoprecipitate. Overview of blood and blood components childrens wisconsin. Sbv was partially reduced to sbiii in blood incubation experiments.
Australian code of good manufacturing practice for human. Australian code of good manufacturing practice for human blood and blood components, human tissue and human cellular therapy products page 6 of 29 v1. The total amount of blood in humans varies with age, sex, weight, body type, and other factors, but a rough average figure for adults is about 60 millilitres per kilogram of body weight. Some blood cells carry oxygen necessary for metabolic reactions, some blood cells fight off invading substances that could destroy your cells, and other blood cells help to form clots, which keep your body from losing too much blood. Regulation and licensing of biological products in countries with newly developing regulatory authorities. This essential fluid carries out the critical functions of transporting oxygen and nutrients to our cells and getting rid of carbon.
Whole blood is a mixture of cellular elements, colloids and crystalloids. This article needs additional citations for verification. Ziser lecture notes, 2005 2 can be found in the blood project now underway to identify every chemical in blood serum plasma with clotting factors removed plasma proteins 8% of blood. Evaluation of the interaction of vanadium with glutathione in human blood components article pdf available in pakistan journal of pharmaceutical sciences 253. Australian code of good manufacturing practice for human blood and blood components, human tissue and human cellular therapy products page 4 of 29 v1. Blood components hereafter referred to as circular is an. The liquid component of the blood in which the following blood cells are suspended. This guidance represents the current thinking of the food and drug administration. Certain white blood cells mature in the lymph nodes, spleen, and thymus gland. Circular of information for the use of human blood and blood components. Blood cells are produced by bone marrow within the bone. The plasma is the light yellow liquid portion of the blood and is about 90% water. White blood cells leukocytes help fight infections and aid in the immune process. These include red blood cells, white blood cells, and platelets.
206 1483 590 430 847 767 1466 1511 1064 995 633 470 1575 423 1534 487 1246 24 1061 1441 532 377 356 171 1107 73 943 334 12 1020 1387 1556 37 299 436 1470 446 879 1466 1227 219 508 1362 1388 306 924 657